Industrially relevant features of plant systems include proper eukaryotic protein processing, inherent safety due to lack of adventitious agents dangerous for humans, fast and easily scalable production, and competitive manufacturing costs. Notably, magnICON® exceeds other similar plant-based technologies in terms of speed, yield and production costs (Tusé et al., 2014 ). The magnICON® technology is a transient technology that does not require stable, genetic modification of plants, therefore resulting in faster and more flexible production. Production of green plant biomass is a routine agricultural operation carried out in standard greenhouses that is physically and timely separated from the stage of recombinant protein production. The decision what to produce in a ready plant batch can be taken just before the scheduled downstream processing operations by using any previously established expression construct encoding the recombinant protein of interest. Furthermore, the magnICON® technology was developed with consideration of human, environmental and product safety by applying efficient measures for each biological component and each manufacturing step.
